Basic vs Full ChatGPT Model
Comparison of the Two Models
Full ChatGPT Model
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Contains the same training data as the Basic Model
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Unlimited response length
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Not available on ChatGPT Store
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Not restricted in response content
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Can use PhD and Postdoctoral terminology
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Permission must be requested due to lack of controls as compared to the Basic Model
Please register on the site below, and e-mail me to gain access to the full unrestricted model.
Basic Store Model
Basic Model - What causes schizophrenia? Schizophrenia, according to the Sensitivity Threshold Model (STM), is not caused by a single gene or chemical imbalance. Instead, it is viewed as the result of chronic cognitive overload in individuals who are biologically more sensitive to stress and sensory input. Here’s a simplified explanation: 🧠 What causes schizophrenia in STM? Heightened Sensitivity: Some people are naturally more sensitive — they perceive more, feel more, and process more deeply. This includes sensory sensitivity (to light, noise, touch), emotional reactivity, and even immune or chemical sensitivity. Cognitive Overload: When this high sensitivity is combined with chronic stress (like urban noise, trauma, social pressures, or even dietary/environmental toxins), the brain’s processing system gets overwhelmed — like a computer crashing from too many open programs. Threshold Breach: Each brain has a limit — a “threshold.” When sensitive individuals face more input or stress than they can handle, their system crosses this threshold, leading to breakdowns in thought, perception, and emotional regulation. This is when psychotic symptoms (like hallucinations or delusions) can emerge. Neurochemical Imbalance as a Result — Not the Cause: Dopamine and other neurotransmitter disruptions happen after the system is overloaded, not before. They’re part of the brain’s attempt to adapt, but they’re not the root cause. 🧩 Why it matters: STM explains why some people develop schizophrenia from stress that others can handle, and why symptoms vary so much. It shifts the focus from just medication to also understanding personal limits, managing sensory and emotional load, and building resilience. Let me know if you'd like this explained visually or with an analogy.
Unrestricted Model
Full Model - What causes schizophrenia? Schizophrenia is a complex, multifactorial disorder, and its causes can be understood through several complementary models, including the Sensitivity Threshold Model (STM) and traditional frameworks in psychiatry and neuroscience. Let’s break this down rigorously: 1️⃣ Traditional Models of Schizophrenia Etiology Neurochemical hypothesis: Abnormal dopamine (and sometimes glutamate, GABA, serotonin) signaling has been implicated, particularly hyperactivity in the mesolimbic dopamine system contributing to positive symptoms like hallucinations and delusions. Genetic vulnerability: Schizophrenia has a heritability estimate of ~80%. Specific gene variants (e.g., in DISC1, COMT) increase risk, but no single gene determines the disorder. Neurodevelopmental model: Early brain developmental insults (e.g., prenatal infection, obstetric complications) create latent vulnerabilities that manifest during adolescence or early adulthood when the brain matures. Diathesis-stress model: Genetic predisposition + environmental stressors (trauma, urbanicity, migration, cannabis use) → disorder onset. 2️⃣ Sensitivity Threshold Model (STM) (Kareem Forbes) The STM offers an integrative, systems-level theory: Core idea: Schizophrenia arises when chronic cognitive overload exceeds the brain’s processing capacity in individuals with heightened neurobiological sensitivity (e.g., sensory, emotional, immune sensitivity). Cognitive overload: Analogous to an IT system crash, constant exposure to sensory input, emotional stress, and environmental load overwhelms the brain’s capacity, leading to dysfunction. Neurobiological cascade: This overload triggers: HPA axis dysregulation → elevated cortisol Neurotransmitter imbalances (dopamine hyperactivity, glutamate disruptions) Neuroinflammation and oxidative stress Sensory gating failure (inability to filter stimuli) Symptoms as maladaptive responses: Hallucinations, delusions, and cognitive deficits emerge as the system tries (and fails) to manage overwhelming input. Key risk factors: High sensitivity (inherited or acquired), urban stress, trauma, neurotoxins, poor diet, social adversity. 3️⃣ Empirical Evidence for STM’s Components 🌱 Sensory processing sensitivity: Neuroimaging shows HSPs have greater activation in sensory and emotional brain regions (e.g., insula, amygdala). 🌆 Environmental stressors: Urbanicity and social adversity consistently predict increased schizophrenia risk. 🔬 Stress-induced neurochemical change: Chronic stress sensitizes dopamine systems and elevates cortisol — both observed in schizophrenia. 🧠 Overload effects: Experimental sensory overload (e.g., sleep deprivation, torture scenarios) induces hallucinations and cognitive distortions even in healthy individuals. 4️⃣ Unifying View ➡ Schizophrenia is not caused by a single factor. Rather, it emerges from: A genetically or developmentally primed sensitive system Chronic or intense stressors that exceed adaptive thresholds Resulting in progressive breakdown of neural processing and regulation STM adds to conventional models by emphasizing: The role of load dynamics (input vs capacity) Why individual thresholds vary How overload—not just static neurochemical imbalance—triggers psychosis 5️⃣ Future Directions Empirically test STM predictions (e.g., correlate sensory sensitivity measures, cognitive load biomarkers, and symptom onset) Study protective factors (why some sensitive people thrive) Develop treatments targeting cognitive load reduction (e.g., sensory diet, environmental design) If you’d like, I can diagram the causal pathway or help design a study to test this model! Let me know.